A synthetic peptide for use as a blocking control in assays to test for specificity of LMNB1 antibody, Alternative Names: Lamin B1 control peptide, Lamin B1 antibody Blocking Peptide, Anti-Lamin B1 Blocking Peptide, LMNB1 Blocking Peptide, ADLD Blocking Peptide, LMN Blocking Peptide, LMN2 Blocking Peptide, LMNB Blocking Peptide, MGC111419 Blocking Peptide
LAMNB1 encodes for one of the two B type proteins of the nuclear lamina, B1. The Vertebrate lamins consist of two types, A and B. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression.