Presenilin 1 (PSEN1) Peptide
PSEN1
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
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- Antigène Tous les produits Presenilin 1 (PSEN1)
- Presenilin 1 (PSEN1)
- Type de proteíne
- Synthetic
- Origine
- Mammifères
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- EGDPEAQRRV SKNSKYNAES TERESQDTVA ENDDGGFSEE WEAQRDSHLG
- Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of PSEN1 antibody,
Alternative Names: PSEN1 control peptide, PSEN1 antibody Blocking Peptide, Anti-PSEN1 Blocking Peptide, presenilin 1 Blocking Peptide, AD3 Blocking Peptide, FAD Blocking Peptide, PS1 Blocking Peptide, S182 Blocking Peptide, PSEN1, PSEN-1, PSEN 1, PSEN-1 Blocking Peptide, PSEN 1 Blocking Peptide
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- Indications d'application
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C long term.
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- Antigène
- Presenilin 1 (PSEN1)
- Synonymes
- pre1 Peptide, psen Peptide, zfPS1 Peptide, zf-PS1 Peptide, ad3 Peptide, fad Peptide, ps1 Peptide, s182 Peptide, X-PS-beta Peptide, X-PS-alpha Peptide, AD3 Peptide, FAD Peptide, PS-1 Peptide, PS1 Peptide, S182 Peptide, Ad3h Peptide, presenilin 1 Peptide, presenilin 1 L homeolog Peptide, psen1 Peptide, PSEN1 Peptide, Psen1 Peptide, psen1.L Peptide
- Sujet
- Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1, PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes.
- Poids moléculaire
- 53 kDa
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