A synthetic peptide for use as a blocking control in assays to test for specificity of DNAJC2 antibody, Alternative Names: DNAJC2 control peptide, DNAJC2 antibody Blocking Peptide, Anti-DNAJC2 Blocking Peptide, DnaJ, Hsp40 homolog, subfamily C, member 2 Blocking Peptide, MPHOSPH11 Blocking Peptide, MPP11 Blocking Peptide, ZRF1 Blocking Peptide, ZUO1 Blocking Peptide, DNAJC2, DNAJC-2, DNAJC 2, DNAJC-2 Blocking Peptide, DNAJC 2 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
DNAJC2
(DnaJ (Hsp40) Homolog, Subfamily C, Member 2 (DNAJC2))
Sujet
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6.