Periplakin (PPL) Peptide
PPL
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN937909
Aperçu rapide pour Periplakin (PPL) Peptide (ABIN937909)
Antigène
PPL
(Periplakin (PPL))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- EKSRAQEKVT EKEVVKLQND PQLEAEYQQL QEDHQRQDQL REKQEEELSF
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of PPL antibody,
Alternative Names: Periplakin control peptide, Periplakin antibody Blocking Peptide, Anti-Periplakin Blocking Peptide, KIAA0568 Blocking Peptide, MGC134872 Blocking Peptide, PPL Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- PPL (Periplakin (PPL))
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Sujet
- PPL is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling.
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Poids moléculaire
- 205 kDa
Antigène
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