A synthetic peptide for use as a blocking control in assays to test for specificity of EIF3 E antibody, Alternative Names: EIF3E control peptide, EIF3E antibody Blocking Peptide, Anti-EIF3E Blocking Peptide, Eukaryotic Translation Initiation Factor 3 Subunit E Blocking Peptide, EIF3-P48 Blocking Peptide, EIF3S6 Blocking Peptide, INT6 Blocking Peptide, eIF3-p46 Blocking Peptide, EIF3E, EIFE-3, EIFE 3, EIFE-3 Blocking Peptide, EIFE 3 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
EIF3E
(Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))
Sujet
EIF3E belongs to the eIF-3 subunit E family.It is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. EIF3E is required for nonsense-mediated mRNA decay (NMD), It may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. The protein may interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.