Muscleblind-Like 2 (MBNL2) Peptide
MBNL2
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN937993
Aperçu rapide pour Muscleblind-Like 2 (MBNL2) Peptide (ABIN937993)
Antigène
MBNL2
(Muscleblind-Like 2 (MBNL2))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- ENGRVIACFD SLKGRCSREN CKYLHPPTHL KTQLEINGRN NLIQQKTAAA
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of MBNL2 antibody,
Alternative Names: MBNL2 control peptide, MBNL2 antibody Blocking Peptide, Anti-MBNL2 Blocking Peptide, muscleblind-like 2, Drosophila Blocking Peptide, DKFZp781H1296 Blocking Peptide, MBLL Blocking Peptide, MBLL39 Blocking Peptide, MGC120625 Blocking Peptide, MGC120626 Blocking Peptide, MGC120628 Blocking Peptide, PRO2032 Blocking Peptide, MBNL2, MBNL-2, MBNL 2, MBNL-2 Blocking Peptide, MBNL 2 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- MBNL2 (Muscleblind-Like 2 (MBNL2))
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Sujet
- MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).
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Poids moléculaire
- 28 kDa
Antigène
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