A synthetic peptide for use as a blocking control in assays to test for specificity of SIX1 antibody, Alternative Names: SIX1 control peptide, SIX1 antibody Blocking Peptide, Anti-SIX1 Blocking Peptide, sine oculis-related homeobox 1 homolog Drosophila Blocking Peptide, BB138287 Blocking Peptide, SIX1, SIX-1, SIX 1, SIX-1 Blocking Peptide, SIX 1 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
SIX Homeobox 1 (SIX1)
Synonymes
BOS3 Peptide, DFNA23 Peptide, TIP39 Peptide, BB138287 Peptide, six1b Peptide, six2 Peptide, zgc:92332 Peptide, XSix1 Peptide, six1 Peptide, zgc:77345 Peptide, SIX homeobox 1 Peptide, sine oculis-related homeobox 1 Peptide, SIX homeobox 1a Peptide, SIX homeobox 1 L homeolog Peptide, SIX homeobox 1b Peptide, SIX1 Peptide, Six1 Peptide, six1a Peptide, six1.L Peptide, six1b Peptide
Sujet
Six1 is a transcription factor that is involved in regulation of organogenesis. It seems to be required for development of kidney, muscle and inner ear and to be involved in later steps of myogenic differentiation. It may be involved in limb tendon and ligament development. It binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter. It is thought to be regulated by association with Dach and Eya proteins.