A synthetic peptide for use as a blocking control in assays to test for specificity of AKAP10 antibody, Alternative Names: AKAP10 control peptide, AKAP10 antibody Blocking Peptide, Anti-AKAP10 Blocking Peptide, A-kinase anchoring protein 10 Blocking Peptide, Prka Anchor Protein 10 Blocking Peptide, AKAP Blocking Peptide, D-AKAP2 Blocking Peptide, MGC9414 Blocking Peptide, PRKA10 Blocking Peptide
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA, therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.