N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) Peptide
NECAB3
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN938135
Aperçu rapide pour N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3) Peptide (ABIN938135)
Antigène
NECAB3
(N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- ESVEAQSRLC GSRRAGRRAL RSVSRSSTWS PGSSDTGRSS EAEMQWRLQV
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of NECAB3 antibody,
Alternative Names: NECAB3 control peptide, NECAB3 antibody Blocking Peptide, Anti-NECAB3 Blocking Peptide, N-Terminal Ef-Hand Calcium Binding Protein 3 Blocking Peptide, APBA2BP Blocking Peptide, EFCBP3 Blocking Peptide, NIP1 Blocking Peptide, STIP3 Blocking Peptide, SYTIP2 Blocking Peptide, XB51 Blocking Peptide, dJ63M2.4 Blocking Peptide, dJ63M2.5 Blocking Peptide, NECAB3, NECAB-3, NECAB 3, NECAB-3 Blocking Peptide, NECAB 3 Blocking Peptide -
Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))
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Sujet
- The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.
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Poids moléculaire
- 44 kDa
Antigène
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