A synthetic peptide for use as a blocking control in assays to test for specificity of HRG antibody, Alternative Names: HRG control peptide, HRG antibody Blocking Peptide, Anti-HRG Blocking Peptide, Histidine-Rich Glycoprotein Blocking Peptide, DKFZp779H1622 Blocking Peptide, HPRG Blocking Peptide, HRGP Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
HRG
(Histidine-Rich Glycoprotein (HRG))
Sujet
This histidine-rich glycoprotein(HRG) contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.