A synthetic peptide for use as a blocking control in assays to test for specificity of SS18 L1 antibody, Alternative Names: SS18L1 control peptide, SS18L1 antibody Blocking Peptide, Anti-SS18L1 Blocking Peptide, Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 Blocking Peptide, CREST Blocking Peptide, KIAA0693 Blocking Peptide, LP2261 Blocking Peptide, MGC26711 Blocking Peptide, MGC78386 Blocking Peptide, SS18L1, SSL1-18, SSL1 18, SSL1-18 Blocking Peptide, SSL1 18 Blocking Peptide
Synovial sarcomas occur most frequently in the extremities around large joints. More than 90 % of cases have a recurrent and specific chromosomal translocation, t(X,18)(p11.2,q11.2), in which the 5-prime end of the SS18 gene is fused in-frame to the 3-prime end of the SSX1, SSX2, or SSX4 gene. The SS18L1 gene is homologous to SS18.