Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) Peptide
GADD45B
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN938237
Aperçu rapide pour Growth Arrest and DNA-Damage-Inducible, beta (GADD45B) Peptide (ABIN938237)
Antigène
GADD45B
(Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- FCCDNDINIV RVSGMQRLAQ LLGEPAETQG TTEARDLHCL LVTNPHTDAW
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of GADD45 B antibody,
Alternative Names: GADD45B control peptide, GADD45B antibody Blocking Peptide, Anti-GADD45B Blocking Peptide, Growth Arrest And Dna-Damage-Inducible Beta Blocking Peptide, DKFZP566B133 Blocking Peptide, GADD45BETA Blocking Peptide, MYD118 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- GADD45B (Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
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Sujet
- GADD45B is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
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Poids moléculaire
- 18 kDa
Antigène
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