A synthetic peptide for use as a blocking control in assays to test for specificity of HERC5 antibody, Alternative Names: HERC5 control peptide, HERC5 antibody Blocking Peptide, Anti-HERC5 Blocking Peptide, Hect Domain And Rld 5 Blocking Peptide, CEB1 Blocking Peptide, CEBP1 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
HERC5
(Hect Domain and RLD 5 (HERC5))
Sujet
This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4.