Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) Peptide
Aperçu rapide pour Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF) Peptide (ABIN938637)
Antigène
Origine
Source
Application
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Type de proteíne
- Synthetic
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Séquence
- GESYRGLMDH TESGKICQRW DHQTPHRHKF LPERYPDKGF DDNYCRNPDG
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of HGF antibody,
Alternative Names: HGF control peptide, HGF antibody Blocking Peptide, Anti-HGF Blocking Peptide, Hepatocyte Growth Factor Blocking Peptide, Hepapoietin A Scatter Factor Blocking Peptide, F-TCF Blocking Peptide, HGFB Blocking Peptide, HPTA Blocking Peptide, SF Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
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Sujet
- Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69 kDa alpha-chain and 34 kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity.
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Poids moléculaire
- 26 kDa
Antigène
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