Centromere Protein B (CENPB) Peptide
Aperçu rapide pour Centromere Protein B (CENPB) Peptide (ABIN938663)
Antigène
Origine
Source
Application
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Type de proteíne
- Synthetic
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Séquence
- GGEDSDSDSE EEDDEEEDDE DEDDDDDEED GDEVPVPSFG EAMAYFAMVK
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of CENPB antibody,
Alternative Names: CENPB control peptide, CENPB antibody Blocking Peptide, Anti-CENPB Blocking Peptide, Centromere Protein B 80Kda Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- CENPB (Centromere Protein B (CENPB))
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Sujet
- CENPB is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognised by sera from patients with anti-centromere antibodies.
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Poids moléculaire
- 65 kDa
Antigène
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