A synthetic peptide for use as a blocking control in assays to test for specificity of CENPB antibody, Alternative Names: CENPB control peptide, CENPB antibody Blocking Peptide, Anti-CENPB Blocking Peptide, Centromere Protein B 80Kda Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
CENPB
(Centromere Protein B (CENPB))
Synonymes
CENPB Peptide, CENP-B Peptide, centromere protein B Peptide, centromere protein B, 80kDa Peptide, CENPB Peptide, Cenpb Peptide
Sujet
CENPB is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognised by sera from patients with anti-centromere antibodies.