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Fibrillarin (FBL) Peptide

FBL Reactivité: Mammifères Hôte: Synthetic BP, IHC, WB
N° du produit ABIN938665

Aperçu rapide pour Fibrillarin (FBL) Peptide (ABIN938665)

Antigène

Fibrillarin (FBL)

Origine

Mammifères

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
  • Type de proteíne

    Synthetic

    Séquence

    GGGFHSGGNR GRGRGGKRGN QSGKNVMVEP HRHEGVFICR GKEDALVTKN

    Attributs du produit

    A synthetic peptide for use as a blocking control in assays to test for specificity of FBL antibody,
    Alternative Names: Fibrillarin control peptide, Fibrillarin antibody Blocking Peptide, Anti-Fibrillarin Blocking Peptide, FBL Blocking Peptide, Nop1p Blocking Peptide
  • Indications d'application

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20 °C long term.
  • Antigène

    Fibrillarin (FBL)

    Sujet

    FBL is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. FBL contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognise fibrillarin.

    Poids moléculaire

    35 kDa
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