Inhibin, alpha (INHA) Peptide
INHA
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN938770
Aperçu rapide pour Inhibin, alpha (INHA) Peptide (ABIN938770)
Antigène
Inhibin alpha (INHA)
(Inhibin, alpha (INHA))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- GLAQEAEEGL FRYMFRPSQH TRSRQVTSAQ LWFHTGLDRQ GTAASNSSEP
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of INHA antibody,
Alternative Names: Inhibin Alpha control peptide, Inhibin Alpha antibody Blocking Peptide, Anti-Inhibin Alpha Blocking Peptide, INHA Blocking Peptide -
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- Inhibin alpha (INHA) (Inhibin, alpha (INHA))
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Sujet
- INHA joins either the beta A or beta B subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. However, in prostate cancer, expression of the inhibin alpha-subunit gene was suppressed and was not detectable in poorly differentiated tumor cells. Furthermore, because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone.
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Poids moléculaire
- 40 kDa
Antigène
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