A synthetic peptide for use as a blocking control in assays to test for specificity of CCDC50 antibody, Alternative Names: CCDC50 control peptide, CCDC50 antibody Blocking Peptide, Anti-CCDC50 Blocking Peptide, Coiled-Coil Domain Containing 50 Blocking Peptide, C3orf6 Blocking Peptide, DFNA44 Blocking Peptide, YMER Blocking Peptide, CCDC50, CCDC-50, CCDC 50, CCDC-50 Blocking Peptide, CCDC 50 Blocking Peptide
CCDC50 is a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling.