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Coagulation Factor VIII (F8) Peptide

F8 Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN938955
  • Antigène Tous les produits Factor VIII (F8)
    Factor VIII (F8) (Coagulation Factor VIII (F8))
    Type de proteíne
    Synthetic
    Origine
    Mammifères
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    GSKGEKGERG RAGELGEAGP SGEPGVPGDA GMPGERGEAG HRGSAGALGP
    Attributs du produit
    A synthetic peptide for use as a blocking control in assays to test for specificity of F8 antibody,
    Alternative Names: F8 control peptide, F8 antibody Blocking Peptide, Anti-F8 Blocking Peptide, coagulation factor VIII, procoagulant component Blocking Peptide, AHF Blocking Peptide, DXS1253E Blocking Peptide, F8B Blocking Peptide, F8C Blocking Peptide, FVIII Blocking Peptide, HEMA Blocking Peptide, F8, F-8, F 8, F-8 Blocking Peptide, F 8 Blocking Peptide
  • Indications d'application
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C long term.
  • Antigène
    Factor VIII (F8) (Coagulation Factor VIII (F8))
    Synonymes
    fb61d02 Peptide, wu:fb61d02 Peptide, Cf-8 Peptide, Cf8 Peptide, FVIII Peptide, AHF Peptide, DXS1253E Peptide, F8B Peptide, F8C Peptide, HEMA Peptide, coagulation factor VIIi Peptide, coagulation factor VIII Peptide, coagulation factor VIII, procoagulant component Peptide, f7i Peptide, F8 Peptide
    Sujet
    This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
    Poids moléculaire
    63 kDa
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