Coagulation Factor VIII (F8) Peptide
F8
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN938955
382,12 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 20 à 27 jours ouvrables
Aperçu rapide pour Coagulation Factor VIII (F8) Peptide (ABIN938955)
Antigène
Factor VIII (F8)
(Coagulation Factor VIII (F8))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- GSKGEKGERG RAGELGEAGP SGEPGVPGDA GMPGERGEAG HRGSAGALGP
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of F8 antibody,
Alternative Names: F8 control peptide, F8 antibody Blocking Peptide, Anti-F8 Blocking Peptide, coagulation factor VIII, procoagulant component Blocking Peptide, AHF Blocking Peptide, DXS1253E Blocking Peptide, F8B Blocking Peptide, F8C Blocking Peptide, FVIII Blocking Peptide, HEMA Blocking Peptide, F8, F-8, F 8, F-8 Blocking Peptide, F 8 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- Factor VIII (F8) (Coagulation Factor VIII (F8))
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Sujet
- This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
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Poids moléculaire
- 63 kDa
Antigène
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