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Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) Peptide

CACNB4 Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN939035
382,12 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 20 à 27 jours ouvrables

Aperçu rapide pour Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4) Peptide (ABIN939035)

Antigène

CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

Origine

Mammifères

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Type de proteíne

    Synthetic

    Séquence

    GVPDPGTGAS SGTRTPDVKA FLESPWSLDP ASASPEPVPH ILASSRQWDP

    Attributs du produit

    A synthetic peptide for use as a blocking control in assays to test for specificity of CACNB4 antibody,
    Alternative Names: CACNB4 control peptide, CACNB4 antibody Blocking Peptide, Anti-CACNB4 Blocking Peptide, Calcium Channel Voltage-Dependent Beta 4 Subunit Blocking Peptide, CACNB4, CACNB-4, CACNB 4, CACNB-4 Blocking Peptide, CACNB 4 Blocking Peptide
  • Indications d'application

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20 °C long term.
  • Antigène

    CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

    Sujet

    CACNB4 is a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. CACNB4 plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE) and juvenile myoclonic epilepsy (JME).

    Poids moléculaire

    50 kDa
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