A synthetic peptide for use as a blocking control in assays to test for specificity of GRPEL2 antibody, Alternative Names: GRPEL2 control peptide, GRPEL2 antibody Blocking Peptide, Anti-GRPEL2 Blocking Peptide, Grpe-Like 2 Mitochondrial Blocking Peptide, DKFZp451C205 Blocking Peptide, FLJ23713 Blocking Peptide, FLJ33918 Blocking Peptide, Mt-GrpE#2 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
GRPEL2
(GrpE-Like 2, Mitochondrial (GRPEL2))
Sujet
GRPEL2 is an essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. GRPEL2 seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. GRPEL2 stimulates ATPase activity of mt-HSP70. GRPEL2 may also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.