FYVE, RhoGEF and PH Domain Containing 1 (FGD1) Peptide
FGD1
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN939123
Aperçu rapide pour FYVE, RhoGEF and PH Domain Containing 1 (FGD1) Peptide (ABIN939123)
Antigène
FGD1
(FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- HGHRAPGGAG PSEPEHPATN PPGAAPPACA DSDPGASEPG LLARRGSGSA
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of FGD1 antibody,
Alternative Names: FGD1 control peptide, FGD1 antibody Blocking Peptide, Anti-FGD1 Blocking Peptide, FYVE, RhoGEF and PH domain containing 1, faciogenital dysplasia Blocking Peptide, AAS Blocking Peptide, FGDY Blocking Peptide, ZFYVE3 Blocking Peptide, FGD1, FGD-1, FGD 1, FGD-1 Blocking Peptide, FGD 1 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- FGD1 (FYVE, RhoGEF and PH Domain Containing 1 (FGD1))
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Sujet
- FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome.FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs.
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Poids moléculaire
- 106 kDa
Antigène
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