3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) Peptide
HAAO
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN939222
Aperçu rapide pour 3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) Peptide (ABIN939222)
Antigène
HAAO
(3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- HRDVVIRQGE IFLLPARVPH SPQRFANTVG LVVERRRLET ELDGLRYYVG
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of HAAO antibody,
Alternative Names: HAAO control peptide, HAAO antibody Blocking Peptide, Anti-HAAO Blocking Peptide, 3-Hydroxyanthranilate 34-Dioxygenase Blocking Peptide, 3-HAO Blocking Peptide, HAO Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
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Sujet
- 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders.
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Poids moléculaire
- 32 kDa
Antigène
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