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3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) Peptide

HAAO Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN939222
  • Antigène Tous les produits HAAO
    HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
    Type de proteíne
    Synthetic
    Origine
    Mammifères
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    HRDVVIRQGE IFLLPARVPH SPQRFANTVG LVVERRRLET ELDGLRYYVG
    Attributs du produit
    A synthetic peptide for use as a blocking control in assays to test for specificity of HAAO antibody,
    Alternative Names: HAAO control peptide, HAAO antibody Blocking Peptide, Anti-HAAO Blocking Peptide, 3-Hydroxyanthranilate 34-Dioxygenase Blocking Peptide, 3-HAO Blocking Peptide, HAO Blocking Peptide
  • Indications d'application
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C long term.
  • Antigène
    HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))
    Synonymes
    Afu2g17450 Peptide, 0610007K21Rik Peptide, 0610012J07Rik Peptide, 3-HAO Peptide, 3-HAOxase Peptide, 3HAO Peptide, zgc:103585 Peptide, HAO Peptide, 3-hydroxyanthranilate 3,4-dioxygenase Peptide, 3-hydroxyanthranilate 3,4-dioxygenase L homeolog Peptide, SPO1774 Peptide, CNB05620 Peptide, AFUA_2G17450 Peptide, Bcep18194_C7641 Peptide, Kfla_5491 Peptide, Micau_4935 Peptide, RBRH_03005 Peptide, Krodi_1278 Peptide, haao Peptide, HAAO Peptide, Haao Peptide, haao.L Peptide
    Sujet
    3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders.
    Poids moléculaire
    32 kDa
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