4-Aminobutyrate Aminotransferase (ABAT) Peptide
ABAT
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN939395
Aperçu rapide pour 4-Aminobutyrate Aminotransferase (ABAT) Peptide (ABIN939395)
Antigène
ABAT
(4-Aminobutyrate Aminotransferase (ABAT))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- IIVEPIQSEG GDNHASDDFF RKLRDIARKH GCAFLVDEVQ TGGGCTGKFW
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of ABAT antibody,
Alternative Names: ABAT control peptide, ABAT antibody Blocking Peptide, Anti-ABAT Blocking Peptide, 4-Aminobutyrate Aminotransferase Blocking Peptide, GABA-AT Blocking Peptide, GABAT Blocking Peptide, NPD009 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- ABAT (4-Aminobutyrate Aminotransferase (ABAT))
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Sujet
- 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50 kDa subunits complexed to pyridoxal-5-phosphate. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde.
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Poids moléculaire
- 55 kDa
Antigène
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