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Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11) Peptide

PARP11 Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN939406
  • Antigène Tous les produits PARP11
    PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
    Type de proteíne
    Synthetic
    Origine
    Mammifères
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    IKHGNTFQIH GVSLQQRHLF RTYKSMFLAR VLIGDYINGD SKYMRPPSKD
    Attributs du produit
    A synthetic peptide for use as a blocking control in assays to test for specificity of PARP11 antibody,
    Alternative Names: PARP11 control peptide, PARP11 antibody Blocking Peptide, Anti-PARP11 Blocking Peptide, Adp-Ribose Polymerase 11 Blocking Peptide, C12orf6 Blocking Peptide, DKFZp779H0122 Blocking Peptide, Poly (ADP-ribose) polymerase 11 Blocking Peptide, PARP11, PARP-11, PARP 11, PARP-11 Blocking Peptide, PARP 11 Blocking Peptide
    Purification
    Serum
  • Indications d'application
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C long term.
  • Antigène
    PARP11 (Poly (ADP-Ribose) Polymerase Family, Member 11 (PARP11))
    Synonymes
    5330431N24Rik Peptide, AI851877 Peptide, ARTD11 Peptide, HIN1L Peptide, C12orf6 Peptide, parp11 Peptide, MGC82612 Peptide, PARP11 Peptide, RGD1561791 Peptide, poly (ADP-ribose) polymerase family, member 11 Peptide, poly(ADP-ribose) polymerase family member 11 Peptide, poly(ADP-ribose) polymerase family member 11 S homeolog Peptide, poly(ADP-ribose) polymerase family member 11 L homeolog Peptide, Parp11 Peptide, PARP11 Peptide, parp11.S Peptide, parp11.L Peptide, parp11 Peptide
    Sujet
    PARP1 encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
    Poids moléculaire
    39 kDa
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