A synthetic peptide for use as a blocking control in assays to test for specificity of ACTN2 antibody, Alternative Names: ACTN2 control peptide, ACTN2 antibody Blocking Peptide, Anti-ACTN2 Blocking Peptide, ACTN2, ACTN-2, ACTN 2, ACTN-2 Blocking Peptide, ACTN 2 Blocking Peptide
ACTN2
Reactivité: Humain, Souris, Poulet, Boeuf (Vache), Rat
Hôte: Synthetic
BP
Indications d'application
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
ACTN2
(Actinin, alpha 2 (ACTN2))
Sujet
The alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of alpha-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibres, while ACTN3 expression is restricted to a subset of type 2 fibres. Murine Actn2 and Actn3 are differentially expressed, spatially and temporally, during embryonic development and, in contrast to humans, alpha-actinin-2 expression does not completely overlap alpha-actinin-3 in postnatal skeletal muscle, suggesting independent function.