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Bone Morphogenetic Protein 10 (BMP10) Peptide

BMP10 Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN939752
382,12 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 20 à 27 jours ouvrables

Aperçu rapide pour Bone Morphogenetic Protein 10 (BMP10) Peptide (ABIN939752)

Antigène

BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Origine

Mammifères

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Type de proteíne

    Synthetic

    Séquence

    KFATDRTSMP SANIIRSFKN EDLFSQPVSF NGIRKYPLLF NVSIPHHEEV

    Attributs du produit

    A synthetic peptide for use as a blocking control in assays to test for specificity of Bmp10 antibody,
    Alternative Names: Bmp10 control peptide, Bmp10 antibody Blocking Peptide, Anti-Bmp10 Blocking Peptide, bone morphogenetic protein 10 Blocking Peptide, Bmp10 Blocking Peptide, Bmp10, Bmp-10, Bmp 10, Bmp-10 Blocking Peptide, Bmp 10 Blocking Peptide
  • Indications d'application

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20 °C long term.
  • Antigène

    BMP10 (Bone Morphogenetic Protein 10 (BMP10))

    Sujet

    Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth.

    Poids moléculaire

    48 kDa
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