A synthetic peptide for use as a blocking control in assays to test for specificity of PCBP2 antibody, Alternative Names: PCBP2 control peptide, PCBP2 antibody Blocking Peptide, Anti-PCBP2 Blocking Peptide, Poly rC binding protein 2 Blocking Peptide, HNRPE2 Blocking Peptide, MGC110998 Blocking Peptide, hnRNP-E2 Blocking Peptide, PCBP2, PCBP-2, PCBP 2, PCBP-2 Blocking Peptide, PCBP 2 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
PCBP2
(Poly(rC) Binding Protein 2 (PCBP2))
Sujet
PCBP2 appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly(rC)-binding proteins. This protein together with PCBP-1 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.