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Poly(rC) Binding Protein 2 (PCBP2) Peptide

PCBP2 Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN939849

Aperçu rapide pour Poly(rC) Binding Protein 2 (PCBP2) Peptide (ABIN939849)

Antigène

PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

Origine

Mammifères

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Type de proteíne

    Synthetic

    Séquence

    KKGESVKKMR EESGARINIS EGNCPERIIT LAGPTNAIFK AFAMIIDKLE

    Attributs du produit

    A synthetic peptide for use as a blocking control in assays to test for specificity of PCBP2 antibody,
    Alternative Names: PCBP2 control peptide, PCBP2 antibody Blocking Peptide, Anti-PCBP2 Blocking Peptide, Poly rC binding protein 2 Blocking Peptide, HNRPE2 Blocking Peptide, MGC110998 Blocking Peptide, hnRNP-E2 Blocking Peptide, PCBP2, PCBP-2, PCBP 2, PCBP-2 Blocking Peptide, PCBP 2 Blocking Peptide

    Purification

    Serum
  • Indications d'application

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20 °C long term.
  • Antigène

    PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))

    Sujet

    PCBP2 appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly(rC)-binding proteins. This protein together with PCBP-1 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability.

    Poids moléculaire

    39 kDa
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