A synthetic peptide for use as a blocking control in assays to test for specificity of C1 orf166 antibody, Alternative Names: C1ORF166 control peptide, C1ORF166 antibody Blocking Peptide, Anti-C1ORF166 Blocking Peptide, FLJ12875 Blocking Peptide, RP.2 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
MUL1
(Mitochondrial E3 Ubiquitin Protein Ligase 1 (MUL1))
Sujet
C1orf166 encodes an ubiquitin-protein ligase that plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.