A synthetic peptide for use as a blocking control in assays to test for specificity of CARS antibody, Alternative Names: CARS control peptide, CARS antibody Blocking Peptide, Anti-CARS Blocking Peptide, Cysteinyl-tRNA Synthetase Blocking Peptide
CARS is a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer.