Mevalonate Kinase (MVK) Peptide
MVK
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN940193
Aperçu rapide pour Mevalonate Kinase (MVK) Peptide (ABIN940193)
Antigène
MVK
(Mevalonate Kinase (MVK))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- LAVLAFLYLY LSICRKQRAL PSLDIVVWSE LPPGAGLGSS AAYSVCLAAA
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of MVK antibody,
Alternative Names: MVK control peptide, MVK antibody Blocking Peptide, Anti-MVK Blocking Peptide, Mevalonate Kinase Blocking Peptide, LRBP Blocking Peptide, MVLK Blocking Peptide -
Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- MVK (Mevalonate Kinase (MVK))
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Sujet
- MVK is the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash.
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Poids moléculaire
- 42 kDa
Antigène
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