A synthetic peptide for use as a blocking control in assays to test for specificity of CD8 B antibody, Alternative Names: CD8B control peptide, CD8B antibody Blocking Peptide, Anti-CD8B Blocking Peptide, CD8b molecule Blocking Peptide, CD8B1 Blocking Peptide, LYT3 Blocking Peptide, Leu2 Blocking Peptide, Ly3 Blocking Peptide, MGC119115 Blocking Peptide, CD8B, CD-8B, CDA 8, CD-8B Blocking Peptide, CD 8B Blocking Peptide
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8B is the CD8 beta chain isoforms.