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Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Peptide

SUV39H2 Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN940256

Aperçu rapide pour Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) Peptide (ABIN940256)

Antigène

SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))

Origine

Mammifères

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • Type de proteíne

    Synthetic

    Séquence

    LDTRLPRIAL FSTRTINAGE ELTFDYQMKG SGDISSDSID HSPAKKRVRT

    Attributs du produit

    A synthetic peptide for use as a blocking control in assays to test for specificity of SUV39 H2 antibody,
    Alternative Names: SUV39H2 control peptide, SUV39H2 antibody Blocking Peptide, Anti-SUV39H2 Blocking Peptide, Suppressor Of Variegation 3-9 Homolog 2 Blocking Peptide, FLJ23414 Blocking Peptide, KMT1B Blocking Peptide, SUV39H2, SUVH2-39, SUVH2 39, SUVH2-39 Blocking Peptide, SUVH2 39 Blocking Peptide
  • Indications d'application

    Optimal conditions should be determined by the investigator

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.

    Buffer

    PBS

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20 °C long term.
  • Antigène

    SUV39H2 (Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2))

    Sujet

    SUV39H2 is a histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats.

    Poids moléculaire

    40 kDa
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