A synthetic peptide for use as a blocking control in assays to test for specificity of TIPARP antibody, Alternative Names: TIPARP control peptide, TIPARP antibody Blocking Peptide, Anti-TIPARP Blocking Peptide, Tcdd-Inducible Poly Blocking Peptide, Adp-Ribose Polymerase Blocking Peptide, DDF1 Blocking Peptide, DKFZP434J214 Blocking Peptide, DKFZp686N0351 Blocking Peptide, DKFZp686P1838 Blocking Peptide, FLJ40466 Blocking Peptide, PARP-1 Blocking Peptide, PARP-7 Blocking Peptide, PARP7 Blocking Peptide
TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor, repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.