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alpha-2-Macroglobulin (A2M) (N-Term) Peptide

A2M Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN972683

Aperçu rapide pour alpha-2-Macroglobulin (A2M) (N-Term) Peptide (ABIN972683)

Antigène

alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Origine

Humain

Source

  • 3
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Séquence

    PVPGHVTVSI CRKYSDASDC HGEDSQAFCE KFSGQLNSHG CFYQQVKTKV

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-A2M Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

    Sujet

    Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.

    Alias Symbols: CPAMD5, DKFZp779B086, FWP007, S863-7, A2MD

    Protein Interaction Partner: ADAM19,ADAMTS1,AMBP,ANXA6,APOE,ATF7IP,B2M,C11orf58,CELA1,CTSB,CTSE,HSPA5,IL10,IL1B,KLK2,KLK3,LCAT,LEP,LRP1,LYZ,MMP2,MYOC,NGF,PAEP,PDGFA,PDGFB,SHBG,TGFBI,STAT3,ADAMTS1,AMBP,ANXA7,APOE,B2M,C11orf58,CDC42,CDK2AP2,CDKN1A,CPB2,GEM,GRB2,H2AFX,HMOX2,HSPA5,IL10,IL4,KLK13,KLK3,LCAT,LEP,LRP1,MMP2,NGF,NUDT21,PAEP,RAP1B,RPP14,SEPT8,SMN1,TGIF1,TK1,TNFRSF14,TSC22D1,TTR,UFD1L

    Protein Size: 1474

    Poids moléculaire

    161 kDa

    ID gène

    2

    NCBI Accession

    NM_000014, NP_000005

    UniProt

    P01023
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