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Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (Middle Region) Peptide

ACCN1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN972799
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 15 à 22 jours ouvrables

Aperçu rapide pour Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1) (Middle Region) Peptide (ABIN972799)

Antigène

ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

Origine

Humain

Source

  • 6
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-ACCN1 antibody (Catalog #: ARP35537_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    ACCN1 (Amiloride-Sensitive Cation Channel 1, Neuronal (ACCN1))

    Sujet

    ACCN1 is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium.This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified.

    Alias Symbols: ACCN, ASIC2, ASIC2a, BNC1, BNaC1, MDEG, hBNaC1, ACCN1

    Protein Interaction Partner: PICK1,PICK1,ACCN2,ACCN3,PICK1,STOM,ACCN3,Pick1,STOML1

    Protein Size: 512

    Poids moléculaire

    58 kDa

    ID gène

    40

    NCBI Accession

    NM_001094, NP_001085

    UniProt

    Q16515
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