Alkaline Ceramidase 1 (ACER1) (C-Term) Peptide
ACER1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN972812
Aperçu rapide pour Alkaline Ceramidase 1 (ACER1) (C-Term) Peptide (ABIN972812)
Antigène
ACER1
(Alkaline Ceramidase 1 (ACER1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Séquence
- ITFPYGMVTM ALVDANYEMP GETLKVRYWP RDSWPVGLPY VEIRGDDKDC
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-ACER1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ACER1 (Alkaline Ceramidase 1 (ACER1))
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Sujet
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ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.
Alias Symbols: ASAH3, MGC138327, MGC138329, ALKCDase1
Protein Size: 264 -
Poids moléculaire
- 31 kDa
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ID gène
- 125981
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NCBI Accession
- NM_133492, NP_597999
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UniProt
- Q8TDN7
Antigène
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