Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) (Middle Region) Peptide
ADH5
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN972939
Aperçu rapide pour Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) (Middle Region) Peptide (ABIN972939)
Antigène
ADH5
(Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- KSVESVPKLV SEYMSKKIKV DEFVTHNLSF DEINKAFELM HSGKSIRTVV
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-ADH5 Antibody(ARP51767_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))
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Sujet
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This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
Alias Symbols: ADH-3, ADHX, FDH, FALDH, GSNOR, GSH-FDH
Protein Interaction Partner: ADH5,CHD3,ADH5,CHD3,TP53,TP63,TP73
Protein Size: 374 -
Poids moléculaire
- 40 kDa
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ID gène
- 128
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NCBI Accession
- NM_000671, NP_000662
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UniProt
- P11766
Antigène
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