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V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) Peptide

AKT2 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN973084
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 15 à 21 jours ouvrables

Aperçu rapide pour V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) (Middle Region) Peptide (ABIN973084)

Antigène

AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Origine

Humain

Source

  • 9
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-AKT2 antibody (Catalog #: ARP30321_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

    Sujet

    AKT2 belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene encoding AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. AKT2 is a general protein kinase capable of phophorylating several known proteins.This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: PKBBETA, PRKBB, RAC-BETA, PKBB, HIHGHH

    Protein Interaction Partner: APPL1,CHUK,TCL1A,AKT1,AKT1S1,AKT2,APPL1,CHUK,ESR1,FOXO4,FSHR,GSK3B,HSP90AA1,MTCP1,PDPK1,RAB3D,SH3RF1,SLC2A4,TCL1A,TCL1B,TRIB3,TSC2,XIAP,APPL1,CHUK,GSK3B,MTCP1,PRKDC,SH3RF1,TCL1A,TCL1B

    Protein Size: 481

    Poids moléculaire

    56 kDa

    ID gène

    208

    NCBI Accession

    NM_001626, NP_001617

    UniProt

    P31751
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