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Aminolevulinate, delta-, Synthase 1 (ALAS1) Peptide

ALAS1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN973092

Aperçu rapide pour Aminolevulinate, delta-, Synthase 1 (ALAS1) Peptide (ABIN973092)

Antigène

ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Origine

Humain

Source

  • 2
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Attributs du produit

    This is a synthetic peptide designed for use in combination with anti-ALAS1 antibody (Catalog #: ARP54346_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Indications d'application

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Lazareth, Poli, Bignon, Mirmiran, Rabant, Cohen, Schmitt, Puy, Karras, Gouya, Pallet: "Renal Function Decline With Small Interfering RNA Silencing Aminolevulinic Acid Synthase 1 (ALAS1)." dans: Kidney international reports, Vol. 6, Issue 7, pp. 1904-1911, (2021) (PubMed).

  • Antigène

    ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

    Sujet

    Delta-aminolevulinate synthase (ALAS, EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.

    Alias Symbols: ALAS, ALAS3, ALASH, MIG4

    Protein Interaction Partner: STAMBP

    Protein Size: 640

    Poids moléculaire

    70 kDa

    ID gène

    211

    NCBI Accession

    NM_000688, NP_000679

    UniProt

    P13196
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