Aldolase A, Fructose-Bisphosphate (ALDOA) Peptide
Aperçu rapide pour Aldolase A, Fructose-Bisphosphate (ALDOA) Peptide (ABIN973119)
Antigène
Origine
Source
Application
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-ALDOA antibody (Catalog #: ARP48130_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ALDOA (Aldolase A, Fructose-Bisphosphate (ALDOA))
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Sujet
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ALDOA is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia.This gene product, Aldolase A (fructose-bisphosphate aldolase) is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing of this gene results in multiple transcript variants which encode the same protein.
Alias Symbols: ALDA, MGC10942, MGC17716, MGC17767, GSD12
Protein Interaction Partner: ALDOA,ATP6V1E1,DYNLL1,GPD2,MYOC,PLD2,SUMO4,TGM2,TUBB,XRN1,ATP6V1E1,FANCA,OSBPL10,PLD2,USP15,XRN1
Protein Size: 364 -
Poids moléculaire
- 39 kDa
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ID gène
- 226
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NCBI Accession
- NM_000034, NP_000025
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UniProt
- P04075
Antigène
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