ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) (Middle Region) Peptide
ARFGAP1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN973371
Aperçu rapide pour ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) (Middle Region) Peptide (ABIN973371)
Antigène
ARFGAP1
(ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- WRDVTTFFSG KAEGPLDSPS EGHSYQNSGL DHFQNSNIDQ SFWETFGSAE
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-ARFGAP1 Antibody(ARP57150_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
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Sujet
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The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ARF1GAP, HRIHFB2281, MGC39924
Protein Interaction Partner: ARF1,COPA,CSNK1D,CYTH2,KDELR1,RGS2,TMED2,COPA,KDELR1,RGS2
Protein Size: 406 -
Poids moléculaire
- 45 kDa
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ID gène
- 55738
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NCBI Accession
- NM_018209, NP_060679
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UniProt
- Q8N6T3
Antigène
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