Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (C-Term) Peptide
ARNT
Reactivité: Rat
Hôte: Synthetic
BP, WB
N° du produit ABIN973441
Aperçu rapide pour Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) (C-Term) Peptide (ABIN973441)
Antigène
ARNT
(Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
Origine
Rat
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Séquence
- SNEQHVQPTS AQPSSQPEVF QEMLSMLGDQ SNTYNNEEFP DLTMFPPFSE
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-Arnt Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
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Sujet
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Arnt is required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
Alias Symbols: Arnt1, Arnt
Protein Size: 800 -
Poids moléculaire
- 88 kDa
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ID gène
- 25242
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NCBI Accession
- NM_012780, NP_036912
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UniProt
- P41739
Antigène
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