Artemin (ARTN) (Middle Region) Peptide
ARTN
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN973472
Aperçu rapide pour Artemin (ARTN) (Middle Region) Peptide (ABIN973472)
Antigène
ARTN
(Artemin (ARTN))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Séquence
- RTARWCSGRA RRPPPQPSRP APPPPAPPSA LPRGGRAARA GGPGSRARAA
-
Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-ARTN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- ARTN (Artemin (ARTN))
-
Sujet
-
The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ENOVIN, EVN, NBN
Protein Interaction Partner: ARTN,GFRA3,GFRA3
Protein Size: 228 -
Poids moléculaire
- 19 kDa
-
ID gène
- 9048
-
NCBI Accession
- NM_057090, NP_476431
Antigène
-
Vous êtes ici:
