Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) Peptide
ATF4
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN973549
Aperçu rapide pour Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) Peptide (ABIN973549)
Antigène
ATF4
(Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-ATF4 antibody (Catalog #: P100913_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) peptide
ATF4 Reactivité: Humain, Souris, Rat, Porc Hôte: Synthetic BP, Imm
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
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Sujet
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ATF4s a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.
Alias Symbols: CREB-2, CREB2, TAXREB67, TXREB
Protein Interaction Partner: DISC1,DISC1,TRIB3,CCDC106,CEBPB,CEBPG,CREBZF,DAPK3,DDIT3,DISC1,GABBR2,GPS2,GTF2F2,JUN,LDOC1,NFE2L1,NFE2L2,POLR2C,PTCD3,TREX2,TRIB3,TTR,ATF3,CCDC106,CREBBP,Cebpb,DISC1,EIF2A,GABBR1,GABBR2,GPS2,GTF2B,GTF2F2,JUN,LDOC1,POLR2C,PTCD3,TBP,TREX2,TRIB3,TTR
Protein Size: 351 -
Poids moléculaire
- 38 kDa
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ID gène
- 468
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NCBI Accession
- NM_001675, NP_001666
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UniProt
- P18848
Antigène
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