Beta-secretase 1 (BACE1) (N-Term) Peptide
BACE1
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN973702
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 15 à 22 jours ouvrables
Aperçu rapide pour Beta-secretase 1 (BACE1) (N-Term) Peptide (ABIN973702)
Antigène
BACE1
(Beta-secretase 1 (BACE1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Protein Region
- N-Term
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-BACE1 antibody (Catalog #: ARP46851_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BACE1 (Beta-secretase 1 (BACE1))
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Sujet
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Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein. BACE1, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: ASP2, BACE, FLJ90568, HSPC104, KIAA1149
Protein Interaction Partner: ATP1B1,CMPK1,ITM2C,KHSRP,NCSTN,PDIA3,PSAP,RANBP9,APP,ATP1B1,BRI3,CMPK1,CSNK1D,FURIN,GGA2,ITM2C,KHSRP,LRP1,MMP2,NCSTN,PDIA3,PLSCR1,PSAP,PSEN1,RANBP9,SELPLG,NCSTN
Protein Size: 501 -
Poids moléculaire
- 51 kDa
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ID gène
- 23621
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NCBI Accession
- NM_012104, NP_036236
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UniProt
- P56817
Antigène
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