Bardet-Biedl Syndrome 4 (BBS4) (Middle Region) Peptide
BBS4
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits BBS4
- BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- LGIYQKAFEH LGNALTYDPT NYKAILAAGS MMQTHGDFDV ALTKYRVVAC
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-BBS4 Antibody(ARP57696_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
- Synonymes
- CG13232 Peptide, Dmel\\CG13232 Peptide, zgc:152964 Peptide, AW537059 Peptide, AW742241 Peptide, D9Ertd464e Peptide, Bardet-Biedl syndrome 4 Peptide, bardet-biedl syndrome 4 Peptide, Bardet-Biedl syndrome 4 (human) Peptide, BBS4 Peptide, bbs4 Peptide, Bbs4 Peptide
- Sujet
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This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with six other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified.
Alias Symbols: -
Protein Interaction Partner: PCM1,DCTN1,PCM1
Protein Size: 519 - Poids moléculaire
- 58 kDa
- ID gène
- 585
- NCBI Accession
- NM_033028, NP_149017
- UniProt
- Q96RK4
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