B-Cell CLL/lymphoma 2 (BCL2) Peptide
BCL2
Reactivité: Humain
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN973779
Aperçu rapide pour B-Cell CLL/lymphoma 2 (BCL2) Peptide (ABIN973779)
Antigène
Bcl-2 (BCL2)
(B-Cell CLL/lymphoma 2 (BCL2))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-BCL2 antibody (Catalog #: AVARP01005_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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B-Cell CLL/lymphoma 2 (BCL2) peptide
BCL2 Reactivité: Humain, Souris, Rat, Chien Hôte: Synthetic BP, Imm
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Sujet
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The BCL2 gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.
Alias Symbols: Bcl-2, PPP1R50
Protein Interaction Partner: BAD,BAD,BAX,BBC3,BCL2L11,BID,BIK,BIK,BMF,BNIPL,HRK,HRK,RHEB,MOAP1,ATP2A2,BAD,BAG1,BAG3,BAG4,BAK1,BAX,BBC3,BCAP31,BCL2,BCL2L1,BCL2L10,BCL2L11,BCL2L14,BCLAF1,BECN1,BFAR,BID,BIK,BLK,BMF,BNIP1,BNIP2,BNIP3,BNIP3L,BNIPL,CASP3,CASP8,CDK2,CPT1A,CYCS,FKBP8,HRAS,HRK,HSPA1A,ITM2B,ITPR1,KRAS,MAPK1,MAPK11,MAPK14,MAPK3,MAPK8,MOAP1,MYC,NLRP1,NMT2,NR4A1,NRAS,PARP1,PIN1,PKMYT1,PMAIP1,PML,PPP1CA,PPP2CA,PPP2R5A,PPP3CA,PRKACA,PRKCA,PSEN1,PXN,RAD9A,RAF1,RRAS,RTN4,SF1,SMN2,SOD1,SPNS1,TMBIM6,TOMM20,TP53,TP53AIP1,TP53BP2,AVEN,BAD,BAD,BAG1,BAG3,BAG4,BAK1,BAX,BAX,BBC3,BBC3,BBC3,BBC3,BCAP31,BCL2L1,BCL2L10,BCL2L11,BECN1,BID,BID,BIK,BLK,BMF,BNIP1,BNIP2,BNIP3,BNIP3L,BNIPL,Bcl2l11,Becn1,CAPN2,CASP2,CASP3,CASP8,CDK1,DYNLL1,EPHB2,FKBP8,HRK,HSPA1A,IRS1,IRS2,ITM2B,ITPR1,MOAP1,MYC,NR4A1,PARP1,PIN1,PMAIP1,PPP2CA,PPP2R4,PPP2R5A,PPP3CA,PSEN1,RAD9A,RAF1,RRAS,RTN4,RTN4,SERPINB8,SMN1,SOD1,SPNS1,TMBIM6,TOMM20,TP53AIP1,TP53BP2,UBC
Protein Size: 239 -
Poids moléculaire
- 26 kDa
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ID gène
- 596
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NCBI Accession
- NM_000633, NP_000624
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UniProt
- P10415
Antigène
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