Bradykinin Receptor B1 (BDKRB1) (C-Term) Peptide
BDKRB1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN973796
Aperçu rapide pour Bradykinin Receptor B1 (BDKRB1) (C-Term) Peptide (ABIN973796)
Antigène
BDKRB1
(Bradykinin Receptor B1 (BDKRB1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Séquence
- NFFAFTNSSL NPVIYVFVGR LFRTKVWELY KQCTPKSLAP ISSSHRKEIF
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-BDKRB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Bradykinin Receptor B1 (BDKRB1) peptide
BDKRB1 Reactivité: Humain Hôte: Synthetic BP, Imm
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Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
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Sujet
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Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: B1BKR, B1R, BKB1R, BKR1, BRADYB1
Protein Interaction Partner: GNAQ,MEP1A
Protein Size: 353 -
Poids moléculaire
- 40 kDa
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ID gène
- 623
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NCBI Accession
- NM_000710, NP_000701
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UniProt
- P46663
Antigène
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